1.1本试验方法描述了一种用于评估和评估每天在实验动物皮肤上涂抹90天的试验物质毒性特征的程序。 1.2本试验方法无法确定具有长潜伏期（例如致癌性）或缩短寿命的影响。 1.3本试验方法主要用于大鼠、豚鼠或兔子。经适当修改后，可使用其他物种。 1.4本标准无意解决与其使用相关的安全问题（如有）。本标准的用户有责任在使用前制定适当的安全和健康实践，并确定监管限制的适用性。 ====意义和用途====== 本试验方法提供了在短时间内通过皮肤途径反复接触农药或其他化学品可能产生的健康危害信息。它可以提供建立人体暴露安全标准所需的信息。 可以观察到除致死性以外的毒性迹象。 该方法可以提供有关靶器官和可能累积效应的信息。它可能有助于慢性研究剂量的选择。

1.1 This test method describes a procedure for the assessment and evaluation of the toxic characteristics of a test substance that is applied daily to the skin of experimental animals for 90 days. 1.2 This test method is not capable of determining effects that have a long latency period (for example, carcinogenicity) or are life shortening. 1.3 This test method is intended primarily to be used with rats, guinea pigs, or rabbits. Other species may be used with appropriate modifications. 1.4 This standard does not purport to address the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. ====== Significance And Use ====== This test method provides information on health hazards likely to arise from repeated exposure to a pesticide or other chemical by the dermal route over a short time period. It may provide information needed to establish safety criteria for human exposure. Signs of toxicity other than lethality can be observed. This method can provide information on target organs and possible cumulative effects. It may aid in the selection of doses for chronic studies.